{"id":34,"date":"2023-04-20T20:51:43","date_gmt":"2023-04-20T20:51:43","guid":{"rendered":"https:\/\/biomarinmedical-dev-001.azurewebsites.net\/en-us\/?page_id=34"},"modified":"2025-02-28T17:01:30","modified_gmt":"2025-02-28T17:01:30","slug":"phenylketonuria-pku","status":"publish","type":"page","link":"https:\/\/medical.biomarin.com\/en-us\/phenylketonuria-pku\/","title":{"rendered":"Phenylketonuria (PKU)"},"content":{"rendered":"<div id=\"acf-block-6442817da8370\" class=\"hero hero-blue hero-large-first-para\">\n    \t<div class=\"overlay\"><\/div>\n\t<div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n\t\t\t<div class=\"hero-content\">\n\t\t\t    \t\t\t\t\t\t\t\t\t\t\t\t    <h1>Phenylketonuria (PKU)\n<\/h1>\n\t\t\t\t\t\t\t\t\t\t\t\t    <p>Learn more about PKU and BioMarin therapies<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n<div id=\"acf-block-64491d2d50767\" class=\"block wrapped-content\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-64491d2d508a3\" class=\"block-wysiwyg\">\n            <h2>PKU Clinical Program<\/h2>\n<p>Explore select publications on PKU and the clinical research on BioMarin therapies.<\/p>\n    <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-646b4b197dab5\" class=\"block featured-resources-listing\">\n\t<div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n            \t\t\t                <article class=\"resource resource-prescribing-information\">\n                                            <p class=\"resource-type\">Prescribing Information<\/p>\n                                        <div class=\"box prescribing-information\">\n                                                    <h2 class=\"resource-flag\">Full Prescribing Information<\/h2>\n                                                                        <ul>\n                                                                                                                                                                                                                                                                                                <li><a href=\"https:\/\/www.accessdata.fda.gov\/scripts\/cder\/daf\/index.cfm\" target=\"_blank\">View Palynziq (pegvaliase-pqpz) Full Prescribing Information\n<\/a><\/li>\n                                                                                                                                                                                                                                                                                                                                <li><a href=\"https:\/\/www.accessdata.fda.gov\/scripts\/cder\/daf\/index.cfm\" target=\"_blank\">View KUVAN<sup>\u00ae<\/sup> (sapropterin dihydrochloride) Full Prescribing Information\n<\/a><\/li>\n                                                                                    <\/ul>\n                    <\/div>\n                <\/article>\n                                                                                \n                    \n                    \n                                                                                                                                                                                                                            \n                                                                                        \n                                        <article class=\"resource resource-article\">\n                                                    <p class=\"resource-type\">Selected Publications<\/p>\n                                                <div class=\"resource-image\">\n                                                            <div class=\"resource-feature-image\" style=\"background-image: url(https:\/\/medical.biomarin.com\/en-us\/wp-content\/uploads\/sites\/2\/2023\/05\/Selected-Publications-Cover-Image-1024x575.jpg);\"><\/div>\n                                                                                        <p class=\"resource-flag\">Featured<\/p>\n                                                    <\/div>\n                        <div class=\"resource-information\">\n                                                            <div class=\"resource-meta\">\n                                                                            <ul class=\"tags\">\n                                                                                            <li>Publications<\/li>\n                                                                                            <li>Phenylketonuria (PKU)<\/li>\n                                                                                    <\/ul>\n                                                                                                        <\/div>\n                                                                                                                    <h2>Access selected publications on the burden of illness of PKU, sapropterin dihydrochloride, and pegvaliase.\n<\/h2>\n                                                                                <\/div>\n\n                                                                                                                                                                                                        <p><a class=\"button\" href=\"https:\/\/medical.biomarin.com\/en-us\/resource\/selected-publications-pku\/\" target=\"_blank\">View content <\/a><\/p>\n                                            <\/article>\n                                                        \n                    \n                    \n                                                                                                                                                                                                                            \n                                                                                        \n                                        <article class=\"resource resource-article\">\n                                                    <p class=\"resource-type\">Website<\/p>\n                                                <div class=\"resource-image\">\n                                                            <div class=\"resource-feature-image\" style=\"background-image: url(https:\/\/medical.biomarin.com\/en-us\/wp-content\/uploads\/sites\/2\/2025\/02\/ACMG-PKU-Deficiency-Cover-Image_2025.jpg?v=1.0);\"><\/div>\n                                                                                        <p class=\"resource-flag\">Featured<\/p>\n                                                    <\/div>\n                        <div class=\"resource-information\">\n                                                            <div class=\"resource-meta\">\n                                                                            <ul class=\"tags\">\n                                                                                            <li>Publications<\/li>\n                                                                                            <li>Phenylketonuria (PKU)<\/li>\n                                                                                            <li>American College of Medical Genetics and Genomics<\/li>\n                                                                                    <\/ul>\n                                                                                                        <\/div>\n                                                                                                                    <h2>Phenylalanine hydroxylase deficiency diagnosis and management:\n<\/h2>\n                                                                                        <p>A 2023 evidence-based clinical guideline of the American College of Medical Genetics and Genomics (ACMG)<\/p>\n                                                    <\/div>\n\n                                                                                                                                                                                                        <p><a class=\"button\" href=\"https:\/\/www.gimjournal.org\/article\/S1098-3600(24)00223-5\/fulltext\" target=\"_blank\">View content<\/a><\/p>\n                                            <\/article>\n                            \t\t<\/div>\n\t<\/div>\n<\/div>\n\n<div id=\"acf-block-6628637d8cbc1\" class=\"block resources-listing\">\n\t<div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n                            <div class=\"listing-title\">\n                                            <h2>Educational Materials\n<\/h2>\n                                                        <\/div>\n\t\t\t\t\t\t                                    \n                    \n                                                                                                                                                                                                                            \n                                                                                        \n                                        <article class=\"resource resource-video\">\n                                                    <p class=\"resource-type\">Video<\/p>\n                                                <div class=\"resource-split-layout\">\n                            <div class=\"resource-image-block\">\n                                <div class=\"resource-image\">\n                                                                            <div class=\"resource-feature-image\" style=\"background-image: url(https:\/\/medical.biomarin.com\/en-us\/wp-content\/uploads\/sites\/2\/2024\/11\/PKU-Bilder-Video-Cover-Image.jpg?v=1.0);\"><\/div>\n                                                                    <\/div>\n                                                                                                                                                                                                                                                                                                        <p><a class=\"button modal-video permitted\" href=\"https:\/\/player.vimeo.com\/video\/1024904262\" target=\"_self\">Watch now<\/a><\/p>\n                                                            <\/div>\n                            <div class=\"resource-information\">\n                                                                    <div class=\"resource-meta\">\n                                                                                    <ul class=\"tags\">\n                                                                                                    <li>Educational Materials<\/li>\n                                                                                                    <li>Phenylketonuria (PKU)<\/li>\n                                                                                            <\/ul>\n                                                                                                                    <\/div>\n                                                                                                                                    <h2>PKU:<br \/>\nBurden of Illness\n<\/h2>\n                                                                                                    <p><em><strong>Dr. Deborah Bilder<\/strong><\/em><br \/>\nUniversity of Utah<\/p>\n                                                                                                                                                                                                                                                                                                                                        <p><a class=\"button modal-video permitted\" href=\"https:\/\/player.vimeo.com\/video\/1024904262\" target=\"_self\">Watch now<\/a><\/p>\n                                                            <\/div>\n                        <\/div>\n                    <\/article>\n                                    \n                    \n                                                                                                                                                                                                                            \n                                                                                        \n                                        <article class=\"resource resource-article\">\n                                                    <p class=\"resource-type\">Flyer<\/p>\n                                                <div class=\"resource-split-layout\">\n                            <div class=\"resource-image-block\">\n                                <div class=\"resource-image\">\n                                                                            <div class=\"resource-feature-image\" style=\"background-image: url(https:\/\/medical.biomarin.com\/en-us\/wp-content\/uploads\/sites\/2\/2024\/07\/Medical-Education-Cover-Image.jpg?v=1.0);\"><\/div>\n                                                                    <\/div>\n                                                                                                                                                                                                                                                                <p><a class=\"button\" href=\"https:\/\/medical.biomarin.com\/en-us\/wp-content\/uploads\/sites\/2\/2024\/07\/AiCME_PKU_Summary_MMRC-307-00038_EUCAN-PKU-00131.pdf?v=1.0\" target=\"_self\">View content<\/a><\/p>\n                                                            <\/div>\n                            <div class=\"resource-information\">\n                                                                    <div class=\"resource-meta\">\n                                                                                    <ul class=\"tags\">\n                                                                                                    <li>Educational Materials<\/li>\n                                                                                                    <li>Phenylketonuria (PKU)<\/li>\n                                                                                            <\/ul>\n                                                                                                                    <\/div>\n                                                                                                                                    <h2>Answers in CME: Effective Communication Strategies for Improved Phenylketonuria Care\n<\/h2>\n                                                                                                                                                                                                                                                                                                                                <p><a class=\"button\" href=\"https:\/\/medical.biomarin.com\/en-us\/wp-content\/uploads\/sites\/2\/2024\/07\/AiCME_PKU_Summary_MMRC-307-00038_EUCAN-PKU-00131.pdf?v=1.0\" target=\"_self\">View content<\/a><\/p>\n                                                            <\/div>\n                        <\/div>\n                    <\/article>\n                                    \n                    \n                                                                                                                                                                                                                            \n                                                                                        \n                                        <article class=\"resource resource-article\">\n                                                    <p class=\"resource-type\">Resource<\/p>\n                                                <div class=\"resource-split-layout\">\n                            <div class=\"resource-image-block\">\n                                <div class=\"resource-image\">\n                                                                            <div class=\"resource-feature-image\" style=\"background-image: url(https:\/\/medical.biomarin.com\/en-us\/wp-content\/uploads\/sites\/2\/2024\/04\/ex-vivo-PAL-Cover-Image-Type-1-Medical-Website.jpg?v=1.0);\"><\/div>\n                                                                    <\/div>\n                                                                                                                                                                                                                                                                <p><a class=\"button\" href=\"https:\/\/medical.biomarin.com\/en-us\/resource\/statement-regarding-ex-vivo-pal-enzymatic-activity-at-ambient-temperature\/\" target=\"_blank\">View content<\/a><\/p>\n                                                            <\/div>\n                            <div class=\"resource-information\">\n                                                                    <div class=\"resource-meta\">\n                                                                                    <ul class=\"tags\">\n                                                                                                    <li>Educational Materials<\/li>\n                                                                                                    <li>Phenylketonuria (PKU)<\/li>\n                                                                                                    <li>2024<\/li>\n                                                                                            <\/ul>\n                                                                                                                    <\/div>\n                                                                                                                                    <h2>Statement regarding ex vivo PAL enzymatic activity at ambient temperature\n<\/h2>\n                                                                                                                                                                                                                                                                                                                                <p><a class=\"button\" href=\"https:\/\/medical.biomarin.com\/en-us\/resource\/statement-regarding-ex-vivo-pal-enzymatic-activity-at-ambient-temperature\/\" target=\"_blank\">View content<\/a><\/p>\n                                                            <\/div>\n                        <\/div>\n                    <\/article>\n                                    \n                    \n                                                                                                                                                                                                                            \n                                                                                        \n                                        <article class=\"resource resource-article\">\n                                                    <p class=\"resource-type\">Resource<\/p>\n                                                <div class=\"resource-split-layout\">\n                            <div class=\"resource-image-block\">\n                                <div class=\"resource-image\">\n                                                                            <div class=\"resource-feature-image\" style=\"background-image: url(https:\/\/medical.biomarin.com\/en-us\/wp-content\/uploads\/sites\/2\/2023\/04\/PKU_Updated-Congress-graph.png?v=1.0);\"><\/div>\n                                                                    <\/div>\n                                                                                                                                                                                                                                                                <p><a class=\"button\" href=\"https:\/\/medical.biomarin.com\/en-us\/wp-content\/uploads\/sites\/2\/2023\/05\/Neurocognitive-neurological-neuropsychological-manifestations-of-PKU-Type-1-2-Medical-Website_MMRC-PKUG-00179-EUCAN-PKU-00201-March-2025.pdf?v=1.0\" target=\"_self\">View content<\/a><\/p>\n                                                            <\/div>\n                            <div class=\"resource-information\">\n                                                                    <div class=\"resource-meta\">\n                                                                                    <ul class=\"tags\">\n                                                                                                    <li>Educational Materials<\/li>\n                                                                                                    <li>Phenylketonuria (PKU)<\/li>\n                                                                                            <\/ul>\n                                                                                                                    <\/div>\n                                                                                                                                    <h2>Neurocognitive, neurological and neuropsychological manifestations of Phenylketonuria (PKU)\n<\/h2>\n                                                                                                                                                                                                                                                                                                                                <p><a class=\"button\" href=\"https:\/\/medical.biomarin.com\/en-us\/wp-content\/uploads\/sites\/2\/2023\/05\/Neurocognitive-neurological-neuropsychological-manifestations-of-PKU-Type-1-2-Medical-Website_MMRC-PKUG-00179-EUCAN-PKU-00201-March-2025.pdf?v=1.0\" target=\"_self\">View content<\/a><\/p>\n                                                            <\/div>\n                        <\/div>\n                    <\/article>\n                            \t\t<\/div>\n\t<\/div>\n<\/div>\n\n<div id=\"congress-materials\" class=\"block call-to-action block-zero-top\">\n    <div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n\t\t\t<div class=\"box\" style=\"\">\n\t\t\t\t<div class=\"overlay\"><\/div>\n\t\t\t\t<div class=\"cta-content\">\n\t\t\t\t    \t\t\t\t\t<div class=\"cta-content-main\">\n                        <div class=\"content-block\">\n\t\t\t\t\t        \t\t\t\t\t        \t\t\t\t\t\t        <h2 class=\"h3\">PKU Congress Posters and Presentations\n<\/h2>\n\t\t\t\t\t\t    \t\t\t\t\t\t    \t\t\t\t\t\t        <p>Access posters and presentations from recent congresses<\/p>\n\t\t\t\t\t\t    \t\t\t\t\t    <\/div>\n\t\t\t\t\t                                <div class=\"content-block\">\n                                <p><a class=\"button button-ghost button-arrow\" href=\"https:\/\/medical.biomarin.com\/en-us\/phenylketonuria-pku-congress-posters-and-presentations\/\" target=\"_self\">View Congress Posters and Presentations<\/a><\/p>\n                            <\/div>\n\t\t\t\t\t                        <\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-34","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.3 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Phenylketonuria (PKU) - BioMarin Medical EN-US<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/medical.biomarin.com\/en-us\/phenylketonuria-pku\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Phenylketonuria (PKU) - BioMarin Medical 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